Ellingsen Ø et al., Circulation 2017 (SMARTEX-HF, interval vs moderate continuous training in heart failure)

PMID 28082387

Multicentre randomized trial: 261 patients with heart failure and reduced ejection fraction (35% or lower), median age 60, 12 weeks of high-intensity interval training, moderate continuous training, or a recommendation to exercise. Intervals were not superior to moderate continuous training for VO2peak or left ventricular remodelling; differences were not maintained at 52 weeks.