Haddadj R et al. Clinical Walking Speed, Free-Living Walking Cadence, and All-Cause Mortality (JAMA Netw Open, 2026)

PMID 42912394

Whitehall II accelerometer substudy, UK: 4,067 adults, mean age 69.3, median follow-up 11.8 years, 739 deaths. Fully adjusted HR per 1 SD: clinic walking speed 0.77 (0.71–0.84), median wrist cadence 0.83 (0.77–0.90), 95th percentile cadence 0.82 (0.75–0.89). Only clinic speed significantly improved C index over risk factors (0.742 to 0.747). Observational.