
Hormone replacement for absent parathyroids held up over 3.5 years
For adults with hypoparathyroidism who live on calcium and vitamin D tablets: what the longest follow-up of this daily hormone replacement found, and where the evidence still stops.
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For anyone curious about AI tests of biological age: what a new retinal model adds to the oldest risk factor of all, which causes of death it reads best, and what it still cannot tell one person.

4 stories this week: knee osteoarthritis with obesity, a cholesterol-lowering strategy in artery disease, AI screening for heart rhythm problems and clots around arm catheters. Four randomised trials, each with what it does not yet show.
Digest · 4 stories

For pregnant women with low iron weighing an alternative to standard tablets: what the largest blinded test found for mother and baby, and what it leaves open.

For anyone tempted by the best-known anti-ageing drug from mouse studies: what two decades of real-world use in people can say about lifespan, and why it still does not settle the question.

4 stories this week: inherited cholesterol, inflammation in heart and kidney disease, blood pressure after a stroke and anaesthesia in young children. Three large trials from the American Heart Association meeting and one children's trial, each with who was studied and what it does not show.
Digest · 4 stories

For families of people in hospital with alcohol-related liver failure: what a 100-patient trial shows, and why its first-month result is not yet the last word.

For anyone wondering whether the place we live leaves a mark on lifespan: what the Dog Aging Project's initial survival analysis shows in animals that share human environments, and why it does not yet point to a cause.

4 stories this week: a rare liver disease, a leaking heart valve, advanced skin cancer and a painful stiff shoulder. Two trials, an early cell therapy study and a review of 189 trials, each with the limits of what it shows.
Digest · 4 stories

For older people whose kidneys are failing, and for their families: what a randomised comparison can and cannot settle when the choice is dialysis or planned care without it.

4 stories this week: the thyroid, prevention in older age, very high triglycerides and glaucoma screening. A meta-analysis, a large cohort, two phase 3 trials and a population test of AI, each with what it does not yet prove.
Digest · 4 stories

For anyone on or considering this kind of treatment: why a comparison of trial averages cannot tell you whether your own weight loss sets the size of your heart protection.
Articles in this section are educational and are not medical advice, a diagnosis, or a prescription. Consult a qualified professional before acting on anything you read here.