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Publications

Research papers, anchored to PubMed (PMID) or DOI.

Evidence

Any
Very low
Low
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High

Closeness to humans

Any
Cells in vitro
Animals
Early human trials
Proven efficacy in humans

Axis

Any
Genomic instability
Telomere attrition
Epigenetic alterations
Loss of proteostasis
Disabled macroautophagy
Deregulated nutrient sensing
Mitochondrial dysfunction
Cellular senescence
Stem cell exhaustion
Altered intercellular communication
Chronic inflammation
Dysbiosis

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